acute myeloid leukemia with t(8;16)(p11;p13) translocation
Findings
No curated finding names acute myeloid leukemia with t(8;16)(p11;p13) translocation yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A distinct form of Acute myeloid leukemia (AML) in which this chromosomal anomaly is found de novo or in therapy-related AML cases, and is characterized by frequent extramedullary involvement (mainly hepatomegaly, splenomegaly, lymphadenopathies, cutaneous infiltration, but also gum, bone, central nervous system, testicles involvement), severe coagulation disorder (disseminated intravascular coagulopathy or primary fibrinolysis) and poor prognosis. Morphologically, a blast population with a myelomonocytic stage of differentiation is observed.
Definition from the Mondo Disease Ontology (MONDO:0018256), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of
Other names
1 name
Resolves to: acute myeloid leukemia with t(8;16)(p11;p13) translocation
- Also called
- AML with t(8;16)(p11;p13) translocation