acute myeloid leukemia with inv3(p21;q26.2) or t(3;3)(p21;q26.2)
Findings
No curated finding names acute myeloid leukemia with inv3(p21;q26.2) or t(3;3)(p21;q26.2) yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Acute myeloid leukemia with inv(3)(q21;q26.2) or t(3;3)(q21;q26.2) is a subtype of acute myeloid leukemia with recurrent genetic abnormalities characterized by clonal proliferation of myeloid blasts in the bone marrow, blood and, rarely, other tissues. Bone marrow typically shows small, hypolobated megakaryocytes and multilineage dyslplasia. Patients typically present with leukocytosis, anemia, variable platelet counts and a variety of nonspecific symptoms related to ineffective hematopoesis (fatigue, bleeding, bruising, recurrent infections, bone pain) and/or extramedullary site involvement (gingivitis, splenomegaly). High resistance to conventional chemotherapy is reported.
Definition from the Mondo Disease Ontology (MONDO:0018435), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of
Other names
2 names
Resolves to: acute myeloid leukemia with inv3(p21;q26.2) or t(3;3)(p21;q26.2)
- Also called
- AML with inv3(p21;q26.2) or t(3;3)(p21;q26.2)AML with inv3(q21;q26.2) or t(3;3)(q21;q26.2)