acute myeloid leukemia, FLT3 internal tandem duplication
Findings
No curated finding names acute myeloid leukemia, FLT3 internal tandem duplication yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any acute myeloid leukemia that has the chromosomal anomaly FLT3 internal tandem duplication. (A genetic abnormality that arises from duplications of the juxtamembrane portion of the gene and results in constitutive activation of the FLT3 receptor tyrosine kinase protein in early hematopoietic progenitor cells. It is associated with acute myelogenous leukemia where it appears to correlate with a poor prognosis.)
Definition from the Mondo Disease Ontology (MONDO:0100415), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of
Other names
8 names
Resolves to: acute myeloid leukemia, FLT3 internal tandem duplication
- Also called
- AML, Activating FLT3-ITD Gene MutationAML, Activating FLT3-ITD MutationAML, FLT3 internal tandem duplicationAML, FLT3 ITDAML, FLT3-ITDAML, FLT3-ITD Activating MutationAML, FLT3-ITD MutationAML, FLT3/ITD Mutation