Compound
zolasartan
A monocarboxylic acid anion obtained from the deprotonation of the carboxy group and tetrazole NH group of zolasartan. Major microspecies at pH 7.3.
Definition from ChEBI (CHEBI:149524), read 2026-09-23. CC BY 4.0.
Structure
Loading the model…
- Class
- Organic compound, anion
- Formula
- C24H18BrClN6O3
- Mass
- 553.804 g/mol
- Charge
- -2
- InChIKey
- UKNCIPAJCXMEME-UHFFFAOYSA-L
- SMILES
- CCCCc1nc(Cl)c(C(=O)[O-])n1Cc1ccc2oc(-c3ccccc3-c3nnn[n-]3)c(Br)c2c1
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
4 entities
4 entities reached.
0 reported hops4 assembled from the scaffold
What the reference databases state
Statements
7 statements
7 statements · 1 reference database · Subject: zolasartan · Sources: Rhea
- zolasartan is converted to zolarsartan O-beta-D-glucuronosideCompoundRhea RHEA:63732Inferred only
- zolasartan is converted to zolarsartan-1-N-beta-D-glucuronideCompoundRhea RHEA:63744Inferred only
- zolasartan is converted to zolarsartan-2-N-beta-D-glucuronideCompoundRhea RHEA:63748Inferred only
- zolasartan is metabolised by UGT1A10ProteinRhea RHEA:63744Inferred only
- zolasartan is metabolised by UGT1A3ProteinRhea RHEA:63748Inferred only
- zolasartan is metabolised by UGT1A5ProteinRhea RHEA:63744Inferred only
- zolasartan is metabolised by UGT2B7ProteinRhea RHEA:63732Inferred only
Reactions
3 reactions
zolasartan+UDP-alpha-D-glucuronatezolarsartan O-beta-D-glucuronoside+UDP
Catalysed by UGT2B7
Reaction pageLeft to rightBalanced
Rhea RHEA:63732CC BY 4.0Reference data
zolasartan+UDP-alpha-D-glucuronatezolarsartan-1-N-beta-D-glucuronide+UDP
Catalysed by UGT1A5 or UGT1A10
Reaction pageLeft to rightBalanced
Rhea RHEA:63744CC BY 4.0Reference data
zolasartan+UDP-alpha-D-glucuronatezolarsartan-2-N-beta-D-glucuronide+UDP
Catalysed by UGT1A3
Reaction pageLeft to rightBalanced
Rhea RHEA:63748CC BY 4.0Reference data
Other names
1 name
Resolves to: zolasartan
- Systematic name
- 1-({3-bromo-2-[2-(tetrazol-1-id-5-yl)phenyl]-1-benzofuran-5-yl}methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylate