Compound
nitroglycerin
A volatile vasodilator which relieves angina pectoris by stimulating guanylate cyclase and lowering cytosolic calcium. It is also sometimes used for tocolysis and explosives.
Structure
Loading the model…
- Class
- Organic compound
- Formula
- C3H5N3O9
- Mass
- 227.085 g/mol
- Charge
- 0
- InChIKey
- SNIOPGDIGTZGOP-UHFFFAOYSA-N
- SMILES
- O=[N+]([O-])OCC(CO[N+](=O)[O-])O[N+](=O)[O-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Regulatory determinations
LiverTox likelihood score ELiverTox
LiverTox Likelihood Score E — despite extensive use, no evidence that the agent has caused liver injury. Chapter: "Organic Nitrates". Source: LiverTox Master List (NBK571102).
The document·Public Domain (NLM/NIH)·Transcribed, not graded
Statements
2 statements
2 statements · 1 reference database · Subject: nitroglycerin · Sources: Rhea
- nitroglycerin is metabolised by ALDH1B1ProteinRhea RHEA:80155Inferred only
- nitroglycerin is metabolised by ALDH1B1ProteinRhea RHEA:80159Inferred only
Reactions
4 reactions
nitroglycerin+NADPH(4-)1,2-dinitroglycerol+nitrite+NADP(3-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:80131CC BY 4.0Reference data
nitroglycerin+NADPH(4-)1,3-dinitroglycerol+nitrite+NADP(3-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:80135CC BY 4.0Reference data
nitroglycerin+NADH(2-)1,3-dinitroglycerol+nitrite+NAD(1-)
Catalysed by ALDH1B1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:80155CC BY 4.0Reference data
nitroglycerin+NADH(2-)1,2-dinitroglycerol+nitrite+NAD(1-)
Catalysed by ALDH1B1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:80159CC BY 4.0Reference data
Other names
21 names
Resolves to: nitroglycerin
- Also called
- 1,2,3-propanetrioltrinitrate1,2,3-propanetriyl nitrateglycerin trinitrateglycerol trinitrateglycerol, nitric acid triesterGlyceryl trinitrateNGnitroglycerinenitroglycerolNitrostatpropane-1,2,3-triyl trinitratetrinitroglycerintrinitroglycerol
- Systematic name
- 1,2,3-trinitrooxypropane
- Sold as
- MinitranNatisprayNitro-DurNitrolingualNitromistRectogesicTransderm Nitro