cited by PMID:26615509 [rct]; about CHEBI:5855 by its own indexing
cited by PMID:26615509 [observational]; about CHEBI:5855 by its own indexing
cited by PMID:26615509 [cited]; about CHEBI:5855 by its own indexing
cited by PMID:20672296 [cited]; about CHEBI:5855 by its own indexing
cited by PMID:24316697 [observational]; about CHEBI:5855 by its own indexing
cited by PMID:27168073 [mechanism]; about CHEBI:5855 by its own indexing
cited by PMID:19843321 [rct]; about CHEBI:5855 by its own indexing
Discarded — no extractable result42 papers
PMID:40725907claims extracted but refused by the deterministic validatorspipeline:batch2026-09-29
NCT00267293declared_contrast×1 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Group A: Ibuprofen Alone=unmatched, Group B: Ibuprofen and Acetaminophen=unmatched, Group C: Ibuprofen Then Acetaminophen=unmatched)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT00450216declared_contrast×4 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (HZT-501=unmatched, Ibuprofen=unmatched)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT00462722declared_contrast×9 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Placebo Pre and Post Exercise=PLACEBO_COMPARATOR, Ibuprofen Pre and Placebo Post Exercise=EXPERIMENTAL+subject, Placebo Pre and Ibuprofen Post Exercise=EXPERIMENTAL+subject)
NCT00531882declared_contrast×1 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (1-Pioglitazone=EXPERIMENTAL, 2-Simvastatin=unmatched, 3-Ibuprofen 1000-1600 mg Twice Daily (Max 3200 mg/Day)=unmatched)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT00565084declared_contrast×1 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Ibuprofen=unmatched, Placebo 1=unmatched, Placebo 2=unmatched)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT00895843reporting_status×3, declared_contrast×1 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Conventional Ibuprofen=ACTIVE_COMPARATOR+subject, Brufen Retard=EXPERIMENTAL)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01003639declared_contrast×3, outcome_node×1 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Acetazolamide=ACTIVE_COMPARATOR+subject, Sugar Pill=PLACEBO_COMPARATOR+subject)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01035346declared_contrast×7 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Placebo=unmatched, Ibuprofen Sodium=unmatched)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01171794declared_contrast×2 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Ibuprofen=ACTIVE_COMPARATOR+subject, Placebo=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01377441declared_contrast×2 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Ibuprofen=EXPERIMENTAL+subject, Placebo/Saline Solution=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01512160declared_contrast×22, arm_count×4 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (PF-04531083 1000 mg=EXPERIMENTAL, PF-04531083 2000 mg=EXPERIMENTAL, Ibuprofen 400 mg=ACTIVE_COMPARATOR+subject, Placebo=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01529346declared_contrast×16, arm_count×1 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (PF-05089771 150 mg=EXPERIMENTAL, PF-05089771 450 mg=EXPERIMENTAL, PF-05089771 1600 mg=EXPERIMENTAL, Ibuprofen=unmatched, Placebo=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01559259declared_contrast×16 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Placebo=PLACEBO_COMPARATOR, Ibuprofen 200 mg + Acetaminophen 500 mg=unmatched, Ibuprofen 250 mg + Acetaminophen 500 mg=unmatched, Ibuprofen 300 mg + Acetaminophen 500 mg=unmatched, Ibuprofen 400 mg=clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01605903declared_contrast×1 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Treatment With Ibuprofen=EXPERIMENTAL+subject, Treatment With Acetaminophen=ACTIVE_COMPARATOR)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01929031declared_contrast×4 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Placebo=unmatched, Caffeine=unmatched, Ibuprofen=unmatched, Ibuprofen/Caffeine=unmatched)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01943435declared_contrast×3 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Medical Care=ACTIVE_COMPARATOR+subject, Group Exercise=ACTIVE_COMPARATOR, Manual Therapy and Exercise=ACTIVE_COMPARATOR)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02064894declared_contrast×2 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Oral Morphine and Oral Ibuprofen=EXPERIMENTAL, Morphine and Placebo of Ibuprofen=EXPERIMENTAL, Ibuprofen and Placebo of Morphine=ACTIVE_COMPARATOR+subject)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02241512declared_contrast×4 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Ibuprofen=EXPERIMENTAL+subject, Placebo=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02272725declared_contrast×3 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Placebo=PLACEBO_COMPARATOR, Ibuprofen=ACTIVE_COMPARATOR+subject)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02417337declared_contrast×3 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Group I=ACTIVE_COMPARATOR, Group II=EXPERIMENTAL+subject, Group III=EXPERIMENTAL, Group IV=EXPERIMENTAL, Group V=OTHER)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02605187declared_contrast×12 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (No Choice=ACTIVE_COMPARATOR+subject, Choice: Low Protocol=EXPERIMENTAL+subject, Choice: Medium Protocol=EXPERIMENTAL+subject, Choice: High Protocol=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02763059declared_contrast×3 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Group 1- Received Ibuprofen (N=39)=unmatched, Group 2- Received Dexamethasone (N=43)=unmatched, Group 3 - Received Placebo (N=35)=unmatched)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02807623declared_contrast×7, arm_count×1 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Ibuprofen=EXPERIMENTAL+subject, Placebo=PLACEBO_COMPARATOR, Compound Exercise of Push-ups=EXPERIMENTAL)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02912650declared_contrast×19 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Placebo=ACTIVE_COMPARATOR, Ibuprofen 250 mg + Acetaminophen 500 mg=EXPERIMENTAL, Ibuprofen 250 mg=ACTIVE_COMPARATOR+subject, Acetaminophen 650 mg=ACTIVE_COMPARATOR)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03011567declared_contrast×8 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Mild Hypertensive Disorders of Pregnancy- NSAID=unmatched, Mild Hypertensive Disorders of Pregnancy- No NSAID=unmatched)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03186638declared_contrast×1 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Ibuprofen 200 mg BID=unmatched, Placebo=unmatched)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03372382declared_contrast×2 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Ibuprofen Plus Acetaminophen=ACTIVE_COMPARATOR+subject, Ibuprofen Plus Acetaminophen/Hydrocodone=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03399318declared_contrast×4 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Aggressive Antipyretics (AA)=unmatched, Usual Care (UC).=unmatched)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03404518declared_contrast×3 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Norco and Ibuprofen=EXPERIMENTAL, Ibuprofen and Norco=ACTIVE_COMPARATOR+subject)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03441269declared_contrast×3 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (400mg/Dose=ACTIVE_COMPARATOR+subject, 600mg/Dose=ACTIVE_COMPARATOR+subject, 800mg/Dose=ACTIVE_COMPARATOR+subject)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03493945declared_contrast×7 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Phase IIA Dose Expansion (Dose Exp.), Cohort 2, Arm 2.1A=unmatched, All Participants in Phase IIA Dose Expansion and Phase IIB Dose Expansion=unmatched, Phase IIA Dose Expansion, Cohort 2A, Arm 2.3Aclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03545893declared_contrast×1 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Ibuprofen=ACTIVE_COMPARATOR+subject, Ibuprofen + Oxycodone=ACTIVE_COMPARATOR+subject)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03588910declared_contrast×5 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Number of Oxycodone Tablets Typically Prescribed=ACTIVE_COMPARATOR+subject, Half the Number of Oxycodone Tablets Typically Prescribed=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03618823declared_contrast×13, arm_count×1 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Opioid Pain Control Group=unmatched, Non-opioid Pain Control Group=unmatched)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03785756declared_contrast×24, reporting_status×6 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Prolonged Release Group=EXPERIMENTAL+subject, Immediate Release Group=ACTIVE_COMPARATOR+subject, Placebo Group=PLACEBO_COMPARATOR)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03859024declared_contrast×2 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Standard Protocol=ACTIVE_COMPARATOR+subject, Enhanced Recovery Protocol=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03929640declared_contrast×6 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Ibuprofen and Placebo=PLACEBO_COMPARATOR+subject, Ibuprofen and Acetaminophen=ACTIVE_COMPARATOR+subject)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03952650declared_contrast×2, arm_count×1 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (1a - Pilot/Safety: Dosing Interval on Days: 1=unmatched, 2a - Pilot/Safety: Dosing Interval on Days: 1=unmatched)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT04611529declared_contrast×14 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Oral Ibuprofen + Topical Diclofenac=EXPERIMENTAL+subject, Oral Ibuprofen + Topical Placebo=ACTIVE_COMPARATOR+subject, Oral Placebo + Topical Diclofenac=ACTIVE_COMPARATOR)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT05488847declared_contrast×9 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Non Opioid, Multimodal Protocol=unmatched, Opioid Protocol=unmatched)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT06187584declared_contrast×10 — no posted analysis compares a ibuprofen arm with a placebo/no-intervention arm and carries a p-value (Control Group (Opioid Group)=ACTIVE_COMPARATOR+subject, Experimental Group (Nonopioid Group):=EXPERIMENTAL+subject)clinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
Discarded — the wrong intervention29 papers
NCT00627094intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT00802685intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01045993intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01092676intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01172522intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01293968intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01879371intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02013427intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02074709intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02096575intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02268955intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02354092intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02465866intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02521415intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02651324intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02986334intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03080493intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03330119intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03496324intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03509675intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03783702intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03872843intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03900845intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT04491617intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT04905563intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT05017246intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT05479747intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT05737069intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT06938087intervention×1 — no declared intervention names ibuprofenclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
Discarded — another reason, stated per paper9 papers
PMID:38057585no claim extracted — cause not determined (one pass only) — measured: pain-free status at 2 hours, tension-type headache, binary responder outcome pooled as an odds ratio (network meta-analysis)pipeline:batch2026-09-29
PMID:39187775no claim extracted — cause not determined (one pass only) — measured: asthma or asthma-like symptom development or exacerbation in children following ibuprofen exposure, pooled/narrative synthesis by comparator type and population subgrouppipeline:batch2026-09-29
NCT03722238design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT00984815design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT01226095design×1 — studyType OBSERVATIONAL -- only INTERVENTIONAL is extractedclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02294019design×1 — allocation absent -- not randomisedclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02935894design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT03695367design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT04941443design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
Discarded — an endpoint this vocabulary does not hold2 papers
NCT00758836outcome_node×2, declared_contrast×2 — "Percentage of Participants With Pain Freedom at Two Hours Post-dose" names no outcome in the closed vocabularyclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08
NCT02761980outcome_node×3, multiple_analyses×1, measurement×1, declared_contrast×1 — "Time Weighted Sum of Temperature Difference (WSTD) From 0 to 8 Hours" names no outcome in the closed vocabularyclinicaltrials.gov intr search: query.intr=ibuprofen2026-10-08