Discarded — another reason, stated per paper25 papers
NCT00001849design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT00978874design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT01237054design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT01240551design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT01816048
Discarded — an endpoint this vocabulary does not hold13 papers
PMID:37032523no claim extracted — no_outcome_node — measured: white spot lesion prevalence at debonding on subject level, clinical or photographic scoring (Gorelick, EDI), pooled risk ratio | prevalence of white spot lesions at debonding, subject level, Gorelick or EDI scoring from clinical photographs or examinationpipeline:batch2026-10-11
PMID:38898439no claim extracted — no_outcome_node — measured: dental fluorosis severity by Thylstrup-Fejerskov (TF) index, relative risk of severe versus less severe categories | dental fluorosis severity, Thylstrup-Fejerskov index category (TF 5 or above versus TF 4 or below), relative risk by regionpipeline:batch2026-10-11
PMID:38899538no claim extracted — no_outcome_node — measured: dental fluorosis prevalence in permanent teeth, risk ratio or odds ratio across five comparisons | prevalence of dental fluorosis in permanent teeth, RR or OR, children exposed to topical fluoride before age sixpipeline:batch2026-10-11
Discarded — no extractable result10 papers
NCT00759187declared_contrast×1 — no posted analysis compares a fluoride arm with a placebo/no-intervention arm and carries a p-value (Fluoride=unmatched, Fluoride/Triclosan=unmatched, Chlorhexidine Gluconate=unmatched)clinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT00761930declared_contrast×3 — no posted analysis compares a fluoride arm with a placebo/no-intervention arm and carries a p-value (A- Placebo Comparator=unmatched, B - Active Comparator=unmatched, C - Experimental Toothpaste=unmatched)clinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT00762450declared_contrast×1 — no posted analysis compares a fluoride arm with a placebo/no-intervention arm and carries a p-value (Active Comparator=unmatched, Placebo - Silica Control=unmatched, Experimental Toothpaste=unmatched)clinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT00762515declared_contrast×2 — no posted analysis compares a fluoride arm with a placebo/no-intervention arm and carries a p-value (A -Placebo Comparator=unmatched, B- Active Comparator=unmatched)
NCT01991977design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT02448225design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT02645617design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT02752958design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT02953886design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT03007719design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT03235180design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT03242824design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT03778294design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT03824535design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT04184271design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT05258721design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT05470699design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT05779943design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=fluoride2026-09-29
PMID:35104291no claim extracted — cause not determined — DOSED: Silver diamine fluoride (SDF) or SDF plus fluoride varnish, topical, Methods/Results Table 1; comparators placebo, ART, ART+FVpipeline:batch2026-10-11
PMID:39508296no claim extracted — cause not determined — DOSED: Topical silver diamine fluoride (SDF), abstract; comparators include placebo, no treatment, fluoride varnish, sealants and ART (one pass only) — measured: caries increment per surface, new root caries, and caries arrest, pooled mean differencepipeline:batch2026-10-11
PMID:41612282no claim extracted — cause not determined — DOSED: Silver diamine fluoride (10-38% SDF), topical application to carious lesions, Methods/Results; comparator ART with glass ionomer cement (active) (one pass only) — measured: dental caries arrest rate per tooth or surface, probe hardness/absence of symptoms/ICDAS criteria, pooled risk ratiopipeline:batch2026-10-11
PMID:40045047no claim extracted — cause not determined — DOSED: silver diamine fluoride (SDF) applied to root caries in older adults, per abstract; the paper is about SDF, not fluoride as such (one pass only) — measured: tooth survival time after silver diamine fluoride treatment, accelerated failure time modelpipeline:batch2026-10-12
PMID:42418227no claim extracted — cause not determined — DOSED: silver diamine fluoride (Medicaid claims code D1354); a policy and claims-utilization study, no fluoride exposure tested on a health outcomepipeline:batch2026-10-12
no claim extracted — no_outcome_node — measured: enamel surface microhardness recovery after acid erosion, in situ palatal appliance model with bovine enamel specimens, Knoop indentation | enamel surface microhardness recovery after dietary-acid erosion, Knoop microhardness, in situ palatal appliance; acid-resistance ratio
pipeline:batch2026-10-11
PMID:39761023no claim extracted — no_outcome_node — measured: child IQ score across mixed intelligence instruments, pooled standardised mean difference | child IQ score pooled across unharmonised intelligence tests, SMD between exposure groupspipeline:batch2026-10-11
PMID:40604756no claim extracted — no_outcome_node — measured: incidence of initial enamel caries (white spot lesions) around orthodontic brackets, subject-level pooled risk difference | incidence of enamel caries (initial caries / white spot lesions) at subject level in orthodontic patients, risk differencepipeline:batch2026-10-11
PMID:41068882no claim extracted — no_outcome_node — measured: fracture risk (all fractures, fragility fractures) dose-response risk ratio by drinking water fluoride; hip and spine BMD mixed-method dose-response mean difference | fracture risk, all sites and fragility fractures (hip, femur, wrist), dose-response risk ratio per drinking-water fluoride concentration; BMD at hip or femur (hierarchy-selected site) and spine, dose-response mean differencepipeline:batch2026-10-11
PMID:41174838no claim extracted — no_outcome_node — measured: child IQ / general cognitive index score across mixed Wechsler and McCarthy instruments, pooled standardised mean difference | child IQ / cognition score pooled across unharmonised instruments (Wechsler scales, McCarthy MSCA), SMD and regression coefficient per mg/L urinary fluoridepipeline:batch2026-10-11
PMID:40043203no claim extracted — endpoint_near_miss — measured: full-scale raw score (unnormed) on WPPSI-III / WISC-IV, children; the full-scale IQ node names WAIS-RC adult scale | child full-scale IQ raw score on single instruments WPPSI-III (5 y) and WISC-IV (10 y), per doubling of urinary fluoride; node child-iq-across-unharmonised-instruments is a pooled standardised scorepipeline:batch2026-10-12
PMID:40472824no claim extracted — no_outcome_node — measured: caries experience (proportion of 5-year-olds with caries), municipality-level ecological data | dental caries experience (proportion of 5-year-olds with caries), municipality-level aggregatepipeline:batch2026-10-12
PMID:41276066no claim extracted — no_outcome_node — measured: caries trajectory group membership, D2+MFS counts clustered by K-means for longitudinal data | caries trajectory group membership (high vs low) from D2+MFS counts, K-means for longitudinal datapipeline:batch2026-10-12
PMID:41693679no claim extracted — no_outcome_node — measured: time to first dental restoration (dental record procedure codes), Cox proportional hazards | time to first dental restoration, Cox proportional hazards hazard ratiopipeline:batch2026-10-12
PMID:42690660no claim extracted — no_outcome_node — measured: Child Behavior Checklist (CBCL) internalizing and externalizing T scores, parent-report | child internalizing and externalizing behavioural problems, CBCL T scorespipeline:batch2026-10-12
NCT00762853declared_contrast×1 — no posted analysis compares a fluoride arm with a placebo/no-intervention arm and carries a p-value (Fluoride Toothpaste (Placebo)=unmatched, Active Toothpaste=unmatched)clinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT00763048declared_contrast×10 — no posted analysis compares a fluoride arm with a placebo/no-intervention arm and carries a p-value (A - Control Comparator=unmatched, B - Active Comparator=unmatched)clinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT00763256declared_contrast×5 — no posted analysis compares a fluoride arm with a placebo/no-intervention arm and carries a p-value (Active Comparator=unmatched, B - Placebo Comparator=unmatched)clinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT00875212declared_contrast×2 — no posted analysis compares a fluoride arm with a placebo/no-intervention arm and carries a p-value (Control=unmatched, Calcium Glycerophosphate=unmatched, Fluoride=unmatched, Calcium Glycerophosphate and Fluoride=unmatched)clinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT01014143declared_contrast×1 — no posted analysis compares a fluoride arm with a placebo/no-intervention arm and carries a p-value (Fluoride Toothpaste=PLACEBO_COMPARATOR+subject, Total Toothpaste=unmatched, Chlorhexidine Oral Rinse=ACTIVE_COMPARATOR)clinicaltrials.gov intr search: query.intr=fluoride2026-09-29
NCT01072201declared_contrast×3 — no posted analysis compares a fluoride arm with a placebo/no-intervention arm and carries a p-value (Total Toothpaste=EXPERIMENTAL, Ultrabrite Toothpaste=PLACEBO_COMPARATOR+subject)clinicaltrials.gov intr search: query.intr=fluoride2026-09-29