Compound
bradykinin
A nonapeptide messenger that is enzymatically produced from kallidin in the blood where it is a potent but short-lived agent of arteriolar dilation and increased capillary permeability. Bradykinin is also released from mast cells during asthma attacks, from gut walls as a gastrointestinal vasodilator, from damaged tissues as a pain signal, and may be a neurotransmitter.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound, cation
- Formula
- C50H75N15O11
- Mass
- 1062.244 g/mol
- Charge
- +2
- InChIKey
- QXZGBUJJYSLZLT-FDISYFBBSA-P
- SMILES
- NC(=[NH2+])NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H]([NH3+])CCCNC(N)=[NH2+])C(=O)[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
1 statement
1 statement · 1 reference database · Subject: bradykinin · Sources: Rhea
- bradykinin is a substrate of ACEProteinRhea RHEA:71451Inferred only
Reactions
1 reaction
bradykinin+waterL-Phe-L-Arg+bradykinin(1-7)
Catalysed by ACE
Reaction pageLeft to rightBalanced
Rhea RHEA:71451CC BY 4.0Reference data
Other names
2 names
Resolves to: bradykinin
- Systematic name
- 1-[(2S)-2-azaniumyl-5-{[azaniumyl(imino)methyl]amino}pentanoyl]-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-N-[(1S)-4-{[azaniumyl(imino)methyl]amino}-1-carboxylatobutyl]-L-phenylalaninamide1-[(2S)-2-azaniumyl-5-carbamimidamidopentanoyl]-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-N-[(1S)-4-carbamimidamido-1-carboxylatobutyl]-L-phenylalaninamide