Compound
apelin-13
A peptide cation obtained from the protonation of the N-terminus amino group and L-arginyl side chains, and deprotonation of the C-terminus carboxy group of apelin-13. It is the major species at pH 7.3.
Definition from ChEBI (CHEBI:147395), read 2026-09-23. CC BY 4.0.
CHEBI:147395ChEBI
Structure
No depiction stored
No three-dimensional record for this entry.
- Class
- Organic compound, cation
- Formula
- C69H114N23O16S
- Mass
- 1553.883 g/mol
- Charge
- +3
- InChIKey
- XXCCRHIAIBQDPX-PEWBXTNBSA-Q
- SMILES
- CSCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CCCC[NH3+])NC(=O)[C@H](Cc1cncn1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
1 statement
1 statement · 1 reference database · Subject: apelin-13 · Sources: Rhea
- apelin-13 is a substrate of ACE2ProteinRhea RHEA:63564Inferred only
Reactions
1 reaction
apelin-13+waterapelin-12+L-phenylalanine
Catalysed by ACE2
Reaction pageLeft to rightBalanced
Rhea RHEA:63564CC BY 4.0Reference data
Other names
6 names
Resolves to: apelin-13
- Also called
- apelin-13 peptide(3+)Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe(3+)L-Gln-L-Arg-L-Pro-L-Arg-L-Leu-L-Ser-L-His-L-Lys-L-Gly-L-Pro-L-Met-L-Pro-L-Phe(3+)L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine(3+)
- Systematic name
- N(2)-[(2S)-5-amino-2-azaniumyl-5-oxopentanoyl]-N(5)-[amino(iminio)methyl]-L-ornithyl-L-prolyl-N(5)-[amino(iminio)methyl]-L-ornithyl-L-leucyl-L-seryl-L-histidyl-6-azaniumyl-L-norleucylglycyl-L-prolyl-L-methionyl-N-[(1S)-1-carboxylato-2-phenylethyl]-L-prolinamideN2-[(2S)-5-amino-2-azaniumyl-5-oxopentanoyl]-N5-[amino(iminio)methyl]-L-ornithyl-L-prolyl-N5-[amino(iminio)methyl]-L-ornithyl-L-leucyl-L-seryl-L-histidyl-6-azaniumyl-L-norleucylglycyl-L-prolyl-L-methionyl-N-[(1S)-1-carboxylato-2-phenylethyl]-L-prolinamide