Compound

7-oxoglycolithocholate

A cholanic acid conjugate anion that is the conjugate base of 7-oxoglycolithocholic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.

Definition from ChEBI (CHEBI:137818), read 2026-09-23. CC BY 4.0.

CHEBI:137818ChEBI

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Structure

2D depiction · 3D model shown

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A generated conformer of 7-oxoglycolithocholate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C26H40NO5
Mass: 446.608 g/mol
Charge: -1
InChIKey: MOZIKWXTNVWDAB-JPNWVCBHSA-M
SMILES: [H][C@]12CC(=O)[C@]3([H])[C@]([H])(CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCC(=O)NCC(=O)[O-])[C@@]1(C)CC[C@@H](O)C2
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

1 entity

1 entities reached.

0 reported hops1 assembled from the scaffold

HSD11B1ProteinUNIPROT:P28845substrate ofInferred only15 paths15 endpoints

What the reference databases state

Statements

3 statements

3 statements · 1 reference database · Subject: 7-oxoglycolithocholate · Sources: Rhea

Order

7-oxoglycolithocholate is converted to glycochenodeoxycholateCompoundRhea RHEA:65056Inferred only
glycochenodeoxycholate is converted to 7-oxoglycolithocholateCompoundRhea RHEA:65056Inferred only
7-oxoglycolithocholate is a substrate of HSD11B1ProteinRhea RHEA:65056Inferred only

Reactions

3 reactions

glycochenodeoxycholate+NAD(1-)7-oxoglycolithocholate+NADH(2-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:53844CC BY 4.0Reference data
glycochenodeoxycholate+NADP(3-)7-oxoglycolithocholate+NADPH(4-)+hydron
Catalysed by HSD11B1
Reaction pageRight to leftBalance undeterminable
Rhea RHEA:65056CC BY 4.0Reference data
glycoursodeoxycholate+NADP(3-)7-oxoglycolithocholate+NADPH(4-)+hydron
Catalysed by HSD11B1
Reaction pageRight to leftBalance undeterminable
Rhea RHEA:68976CC BY 4.0Reference data

Other names

5 names

Resolves to: 7-oxoglycolithocholate

Also called: 7-oxo-glycolithocholateN-(3alpha-hydroxy-7-oxo-5beta-cholan-24-oyl)glycinateN-(3α-hydroxy-7-oxo-5β-cholan-24-oyl)glycinate
Systematic name: {[(3alpha,5beta)-3-hydroxy-7,24-dioxocholan-24-yl]amino}acetate{[(3α,5β)-3-hydroxy-7,24-dioxocholan-24-yl]amino}acetate