Compound
(20R)-17alpha,20-dihydroxycholesterol
An oxysterol that is cholesterol substituted by hydroxy groups at positions 17 and 20 (the 20R-stereoisomer).
Definition from ChEBI (CHEBI:783), read 2026-09-23. CC BY 4.0.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Chemical structure
- (20R)-17alpha,20-dihydroxycholesterol has the functional parent cholesterolCompoundChEBI CHEBI:783Inferred only
Statements
1 statement
1 statement · 1 reference database · Subject: (20R)-17alpha,20-dihydroxycholesterol · Sources: Human-GEM
- (20R)-17alpha,20-dihydroxycholesterol is metabolised by CYP11A1ProteinHuman-GEM MAR01934Inferred only
Reactions
2 reactions
MAM00592c+proton+NADPH(4-)+dioxygen(20R)-17alpha,20-dihydroxycholesterol+water+NADP(3-)
Catalysed by CYP17A1
Reaction pageLeft to rightBalancedEC 1.14.14.19GO:0005829
Human-GEM MAR01933CC BY 4.0Reference data
(20R)-17alpha,20-dihydroxycholesterol+4proton+2dioxygen+4reduced adrenodoxin17alpha-hydroxypregnenolone+3water+4-methylpentanal+4MAM02663c
Catalysed by CYP11A1
Reaction pageLeft to rightBalance undeterminableEC 1.14.15.6GO:0005829
Human-GEM MAR01934CC BY 4.0Reference data
Other names
3 names
Resolves to: (20R)-17alpha,20-dihydroxycholesterol
- Also called
- 17alpha,20alpha-Dihydroxycholesterol
- Systematic name
- (20R)-cholest-5-ene-3beta,17alpha,20-triol(20R)-cholest-5-ene-3β,17α,20-triol