Compound
10-formyldihydrofolate
Dianion of 10-formyldihydrofolic acid arising from deprotonation of both carboxylic acid functions.
Definition from ChEBI (CHEBI:57452), read 2026-09-23. CC BY 4.0.
Structure
No depiction stored
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- Class
- Organic compound, anion
- Formula
- C20H19N7O7
- Mass
- 469.414 g/mol
- Charge
- -2
- InChIKey
- UXFQDXABPXWSTK-ZDUSSCGKSA-L
- SMILES
- [H]C(=O)N(CC1=Nc2c(nc(N)nc2=O)NC1)c1ccc(C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])cc1
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
2 statements
2 statements · 1 reference database · Subject: 10-formyldihydrofolate · Sources: Rhea
- 10-formyldihydrofolate is a substrate of ATICProteinRhea RHEA:59144Inferred only
- 10-formyldihydrofolate is a substrate of ATICProteinRhea RHEA:62676Inferred only
Reactions
3 reactions
7,8-dihydrofolate+formate+ATP(4-)10-formyldihydrofolate+ADP(3-)+hydrogenphosphate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:24328CC BY 4.0Reference data
10-formyldihydrofolate+5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide+7,8-dihydrofolate
Catalysed by ATIC
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:59144CC BY 4.0Reference data
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-thiocarboxamide+10-formyldihydrofolate6-thio-IMP+7,8-dihydrofolate+water
Catalysed by ATIC
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:62676CC BY 4.0Reference data
Other names
2 names
Resolves to: 10-formyldihydrofolate
- Also called
- 10-formyldihydrofolate dianion
- Systematic name
- N-(4-{N-[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]formamido}benzoyl)-L-glutamate