Compound

1-pyrroline-2-carboxylate

A zwitterion resulting from the transfer of a proton from the carboxy group to the nitrogen of 1-pyrroline-2-carboxylic acid; major species at pH 7.3.

Definition from ChEBI (CHEBI:39785), read 2026-09-23. CC BY 4.0.

CHEBI:39785ChEBI

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Structure

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A generated conformer of 1-pyrroline-2-carboxylate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound
Formula: C5H7NO2
Mass: 113.116 g/mol
Charge: 0
InChIKey: RHTAIKJZSXNELN-UHFFFAOYSA-N
SMILES: O=C([O-])C1=[NH+]CCC1
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

1 entity

1 entities reached.

0 reported hops1 assembled from the scaffold

CRYMProteinUNIPROT:Q14894substrate ofInferred only14 paths7 endpoints

What the reference databases state

Statements

6 statements

6 statements · 1 reference database · Subject: 1-pyrroline-2-carboxylate · Sources: Rhea

Order

1-pyrroline-2-carboxylate is converted to L-prolineCompoundRhea RHEA:20317Inferred only
1-pyrroline-2-carboxylate is converted to L-prolineCompoundRhea RHEA:20321Inferred only
L-proline is converted to 1-pyrroline-2-carboxylateCompoundRhea RHEA:20317Inferred only
L-proline is converted to 1-pyrroline-2-carboxylateCompoundRhea RHEA:20321Inferred only
1-pyrroline-2-carboxylate is a substrate of CRYMProteinRhea RHEA:20317Inferred only
1-pyrroline-2-carboxylate is a substrate of CRYMProteinRhea RHEA:20321Inferred only

Reactions

8 reactions

MAM01742x+FAD1-pyrroline-2-carboxylate+FADH2+proton
Catalysed by DAO
Reaction pageLeft to rightBalancedEC 1.4.3.3GO:0005777
Human-GEM MAR00442CC BY 4.0Reference data
MAM01742c+dioxygen1-pyrroline-2-carboxylate+proton+hydrogen peroxide
Catalysed by DAO
Reaction pageLeft to rightBalancedEC 1.4.3.3GO:0005829
Human-GEM MAR08608CC BY 4.0Reference data
CHEBI:579381-pyrroline-2-carboxylate+water
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:10320CC BY 4.0Reference data
L-proline+NADP(3-)1-pyrroline-2-carboxylate+NADPH(4-)+hydron
Catalysed by CRYM
Reaction pageRight to leftBalance undeterminable
Rhea RHEA:20317CC BY 4.0Reference data
L-proline+NAD(1-)1-pyrroline-2-carboxylate+NADH(2-)+hydron
Catalysed by CRYM
Reaction pageRight to leftBalance undeterminable
Rhea RHEA:20321CC BY 4.0Reference data
CHEBI:57726+A1-pyrroline-2-carboxylate+AH2
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:27306CC BY 4.0Reference data
CHEBI:600411-pyrroline-2-carboxylate+water
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:47624CC BY 4.0Reference data
CHEBI:57726+dioxygen1-pyrroline-2-carboxylate+hydrogen peroxide
Catalysed by DAO
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:78259CC BY 4.0Reference data

Other names

1 name

Resolves to: 1-pyrroline-2-carboxylate

Systematic name: 3,4-dihydro-2H-pyrrolium-5-carboxylate