PapersPMID:9579151
Randomised controlled trial of tyrosine supplementation on neuropsychological performance in phenylketonuria.
What moved
1 findingHow to read these marks →- Increases blood tyrosine concentration
very limited
“Dietary supplements of tyrosine increased plasma tyrosine concentrations; however, no change in test performance was found across the tyrosine and placebo phases of the study.”
- Study
- crossover
- Duration
- 4 weeks
- Dose studied
- L-tyrosine 100 mg/kg body weight/d, four-week phase
- Population
- Individuals with phenylketonuria aged 6 to 28 years on dietary treatment, L-tyrosine versus L-alanine placebo as an adjunct to diet
Study record
- Design
- crossover trial
- Species
- human
- Population
- 21 individuals with phenylketonuria (ages 6 to 28 years, mean 11.3)
- Participants
- 21
- Comparator
- placebo
- Duration
- not reported
- Endpoints measured
- 3
L-tyrosine