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PapersPMID:9579151

Randomised controlled trial of tyrosine supplementation on neuropsychological performance in phenylketonuria.

Archives of disease in childhood1998The record ↗

  1. Finding, very limited evidenceraisesBlood tyrosine concentration

What moved

1 findingHow to read these marks →
  • “Dietary supplements of tyrosine increased plasma tyrosine concentrations; however, no change in test performance was found across the tyrosine and placebo phases of the study.”
    Study
    crossover
    Duration
    4 weeks
    Dose studied
    L-tyrosine 100 mg/kg body weight/d, four-week phase
    Population
    Individuals with phenylketonuria aged 6 to 28 years on dietary treatment, L-tyrosine versus L-alanine placebo as an adjunct to diet

Study record

Design
crossover trial
Species
human
Population
21 individuals with phenylketonuria (ages 6 to 28 years, mean 11.3)
Participants
21
Comparator
placebo
Duration
not reported
Endpoints measured
3