Papers/PMID:42780769
Clinical effects of N-acetylcysteine in ICU patients with respiratory disease: a systematic review and meta-analysis.
Respiratory research & clinical practice2026The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
N-acetyl-L-cysteine — decreases hospital length of stay
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“However, pooled data from 2 studies assessing hospital LOS indicated a significantly shorter LOS in the NAC group than in the control group (MD = −3.84 days; 95% CI: −7.44 to −0.24; Table 3).”
Quoted verbatim from Clinical effects of N-acetylcysteine in ICU patients with respiratory disease: a systematic review and meta-analysis.. - Study
- meta-analysis
- Population
- Critically ill ICU patients with underlying respiratory disease; pooled across 2 randomized trials, NAC in addition to standard care versus placebo or regimens without NAC; reported in days
Effect -3.84 mean difference, 95% CI -7.44 to -0.24
Clinical effects of N-acetylcysteine in ICU patients with respiratory disease: a systematic review and meta-analysis.2026PMID:42780769Permalink