Papers/PMID:42000964
Serum Manganese, Cobalt, Copper, Zinc, Selenium, and Iodine Levels, and the Incidence of Type 2 Diabetes: A Nested Case-control Study.
Biological trace element research2026The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
Zn(2+) — increases type 2 diabetes incidence
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“When stratified by the clinical cutoff for zinc, participants with sufficient zinc levels (≥ 725.5 ng/g for men, ≥ 686.3 ng/g for women) had higher odds of type 2 diabetes compared with those having zinc deficiency (OR: 1.72, 95% CI: 1.07, 2.76).”
Quoted verbatim from Serum Manganese, Cobalt, Copper, Zinc, Selenium, and Iodine Levels, and the Incidence of Type 2 Diabetes: A Nested Case-control Study.. - Study
- case-control
- Population
- Japanese health-checkup adults free of diabetes at baseline, nested case-control (325 cases, 611 matched controls); baseline endogenous serum zinc by ICP-MS, sufficient versus deficient by IZiNCG cutoffs
Effect 1.72 odds ratio, 95% CI 1.07 to 2.76
Serum Manganese, Cobalt, Copper, Zinc, Selenium, and Iodine Levels, and the Incidence of Type 2 Diabetes: A Nested Case-control Study.2026PMID:42000964Permalink