Papers/PMID:41754131
Acute L-Leucine Supplementation and Sprint Exercise Elicit Distinct Appetite and Inflammatory Responses in Persons with Overweight: A Randomized, Counterbalanced, and Crossover Design Study.
Nutrients2026The record
1 finding drawn from this paper, on 1 compound across 1 endpoint, 1 of them null.
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
L-leucine — no detected effect on plasma glucagon-like peptide-1 (GLP-1)
LikelyGrade B, Likely. Human evidence, limited replication or design limits.FindingNull result“There was no clear effect of exercise or L-leucine supplementation on GLP-1, PYY, or ghrelin concentrations A, B, C, D, E, and F, respectively).”
Quoted verbatim from Acute L-Leucine Supplementation and Sprint Exercise Elicit Distinct Appetite and Inflammatory Responses in Persons with Overweight: A Randomized, Counterbalanced, and Crossover Design Study.. - Study
- crossover
- Dose
- 70 mg/kg body weight, three times daily (approximately 5 g/dose for a 70 kg adult)
- Population
- sedentary, overweight, healthy adult men