Papers/PMID:41294251
Effects of Coenzyme Q10 Supplementation on Depressive Symptoms and Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Journal of clinical psychopharmacology2025The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
coenzyme Q10 — no detected effect on subjective fatigue
PreliminaryGrade D, Preliminary. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“No significant benefit was observed for fatigue (SMD: -0.33; 95% CI: -1.38 to 0.72; P =0.54; I2 =89%), based on only 2 trials.”
Quoted verbatim from Effects of Coenzyme Q10 Supplementation on Depressive Symptoms and Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.. - Study
- meta-analysis
- Population
- patients with depression, primary or comorbid with medical illness; pooled across 2 trials
Effects of Coenzyme Q10 Supplementation on Depressive Symptoms and Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.2025PMID:41294251Permalink