Papers/PMID:40565004
Time Does Matter: The Cellular Response to Resveratrol Varies Depending on the Exposure Duration.
International journal of molecular sciences2025The record
2 findings · 1 compound · 2 endpoints · 1 null
What it reported
How to read these marksWhat moved
1 finding
resveratrol — inhibits MTOR
PreliminaryGrade D, Preliminary. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“Moreover, resveratrol decreased mTOR protein levels (both total and phosphorylated forms), particularly after longer incubation times (1 week and 1 month).”
Quoted verbatim from Time Does Matter: The Cellular Response to Resveratrol Varies Depending on the Exposure Duration.. - Study
- in vitro · not in humans
- Dose
- 5 µM, 1 week and 1 month exposure
- Population
- human cardiomyocytes (Celprogen #1311001-09)
Time Does Matter: The Cellular Response to Resveratrol Varies Depending on the Exposure Duration.2025PMID:40565004Permalink
What did not
1 finding
resveratrol — activates SIRT1
PreliminaryGrade D, Preliminary. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“It is noteworthy that, at the selected low concentration of resveratrol, the treatment did not affect Sirt1 protein levels, regardless of the incubation time.”
Quoted verbatim from Time Does Matter: The Cellular Response to Resveratrol Varies Depending on the Exposure Duration.. - Study
- in vitro · not in humans
- Dose
- 5 µM, 1 day, 1 week or 1 month exposure
- Population
- human cardiomyocytes (Celprogen #1311001-09)
Time Does Matter: The Cellular Response to Resveratrol Varies Depending on the Exposure Duration.2025PMID:40565004Permalink