PapersPMID:40343791
Evaluation of alveolar bone preservation and oxidative stress reduction with açai in Wistar rats with induced apical periodontitis.
- findings
- 2
- compound
- 1
- endpoints
- 2
- no difference found
- 1
- Study, every finding
- animal · not in humans
- Dose studied, every finding
- 0.01 mL/g body weight per day by oral gavage for 14 or 28 days, started on day 1 after apical periodontitis induction
What moved
How to read these marks →- Increases reduced glutathione concentration
insufficient
“Both the 14‐ and 28‐day animals of the AP + Açai groups showed higher glutathione (GSH) levels than those in their respective positive control groups (AP14: 16.350 ± 0.947; AP + Açai14: 20.01 ± 0.831; AP28: 14.957 ± 1.363; AP + Açai28: 19.15 ± 0.594; p <.05).”
- Population
- Male Wistar rats with experimentally induced apical periodontitis in both arms (AP + clarified açaí against AP + saline), plasma glutathione, 14-day and 28-day groups reported together
What did not
- No detected effect on total antioxidant capacity
insufficient
“Regarding the TEAC analysis, no difference was observed between the groups (AP14: 1.975 ± 0.018; AP + Açai14: 1.981 ± 0.022; AP28: 1.89 ± 0.009; AP + Açai28: 1.903 ± 0.022; p >.05).”
- Population
- Male Wistar rats with experimentally induced apical periodontitis in both arms (AP + clarified açaí against AP + saline), plasma TEAC by ABTS, 14-day and 28-day groups reported together
Study record
- Design
- animal study, in vivo
- Species
- animal
- Population
- Male Wistar rats (70-90 days old) with experimentally induced apical periodontitis, followed for 14 or 28 days
- Participants
- 32
- Comparator
- placebo
- Duration
- 28 days
- Endpoints measured
- 23