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PapersPMID:40160899

Effects of green tea supplementation on antioxidant status and inflammatory markers in adults: a grade-assessed systematic review and dose-response meta-analysis of randomised controlled trials.

Journal of nutritional science2025The record ↗

findings
2
compound
1
endpoints
2
no difference found
1
  1. Finding, moderate evidencelowersMalondialdehyde (circulating)
  2. Finding, moderate evidenceno difference foundTumour necrosis factor alpha concentration
Study, every finding
meta-analysis
  • “The pooled effect size of the included studies indicated that green tea supplementation could decrease levels of IL-1β (WMD: −0.10 pg/mL; 95% CI: −0.15, −0.06; I2 = 39.3 %; Fig. 2), and MDA (WMD: −0.40 mcmol/L; 95 % CI: −0.63, −0.18; I2 = 99.2 %; Fig. 3).”
    Effect
    −0.4 mean difference, 95% CI −0.63 to −0.18
    Population
    Adults in 11 randomised placebo-controlled trials of green tea, pooled across healthy people and several patient groups

What did not

  • “However, green tea intake did not show a beneficial impact on CRP (WMD: 0.01 mg/L; 95% CI: −0.14, 0.15; I2 = 94.0%; Fig. 2), IL-6 (WMD: −0.34 pg/mL; 95% CI: −0.94, 0.26; I2 = 84.2 %; Fig. 2), or TNF-α (WMD: −0.07 pg/mL; 95% CI: −0.42, 0.28; I2 = 90.3 %; Fig. 2).”
    Effect
    −0.07 mean difference, 95% CI −0.42 to 0.28
    Population
    Adults in 8 randomised placebo-controlled trials of green tea, pooled across healthy people and several patient groups

Study record

Design
meta-analysis
Species
human
Population
Adults (aged 18 or more) in 38 randomised trials of green tea supplementation versus control: healthy individuals, type 2 diabetes, obesity, metabolic syndrome, NAFLD, athletes, older adults and others
Participants
1,985
Comparator
placebo
Duration
not reported
Endpoints measured
23