Papers/PMID:39930713
Acute Administration of 10 mg Methylphenidate on Cognitive Performance and Visual Scanning in Healthy Adults: Randomised, Double-Blind, Placebo-Controlled Study.
Human psychopharmacology2025The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
methylphenidate — increases working memory performance
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.Finding“A significant main effect of treatment was observed for numeric working memory accuracy, whereby accuracy improved (better performance: F(1,96) = 8.76, p = 0.004) following methylphenidate (M = 96.47, SD ± 2.83) administration relative to placebo (M = 94.45, SD ± 4.43, with an odds ratio of 1.67 (95%CI: 1.09–2.57).).”
Quoted verbatim from Acute Administration of 10 mg Methylphenidate on Cognitive Performance and Visual Scanning in Healthy Adults: Randomised, Double-Blind, Placebo-Controlled Study.. - Study
- crossover
- Dose
- 10 mg methylphenidate (Ritalin), single dose
- Population
- Healthy adults aged 21-45 years; single 10 mg dose against placebo in a randomised double-blind crossover with one-week washout; main effect of treatment pooled over the 20-minute and 130-minute assessments
Effect 1.67 odds ratio, 95% CI 1.09 to 2.57
Acute Administration of 10 mg Methylphenidate on Cognitive Performance and Visual Scanning in Healthy Adults: Randomised, Double-Blind, Placebo-Controlled Study.2025PMID:39930713Permalink