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PapersPMID:39519602

Effects of Licorice Functional Components Intakes on Blood Pressure: A Systematic Review with Meta-Analysis and NETWORK Toxicology.

Nutrients2024The record ↗

findings
2
compound
1
endpoints
2
  1. Finding, moderate evidenceno difference foundSystolic blood pressure
  2. Finding, moderate evidenceno difference foundDiastolic blood pressure
Study, every finding
meta-analysis

No finding here moved its endpoint.

What did not

How to read these marks →
  • “Nine RCTs involving LF as the primary licorice intervention (218 participants in the control group and 233 in the intervention group) found no significant effect on SBP or DBP when compared to the control group (SBP: WMD [95% CI] = 0.58 [−1.15, 2.31], p = 0.511; DBP: WMD [95% CI] = 0.17 [−1.53, 1.88], p = 0.843).”
    • No detected effect on systolic blood pressure

      moderate

      Effect
      0.58 mean difference, 95% CI −1.15 to 2.31
      Population
      Pooled participants of nine RCTs in the licorice-flavonoid-dominated stratum; substantial heterogeneity (I2 83.3% for SBP)
    • No detected effect on diastolic blood pressure

      moderate

      Effect
      0.17 mean difference, 95% CI −1.53 to 1.88
      Population
      Pooled participants of nine RCTs in the licorice-flavonoid-dominated stratum; substantial heterogeneity (I2 91.2% for DBP)

Study record

Design
meta-analysis
Species
human
Population
Participants of randomized controlled trials of licorice or licorice functional components (glycyrrhizic acid-dominated or licorice flavonoid-dominated interventions)
Participants
541
Comparator
not stated in the paper
Duration
not reported
Endpoints measured
29