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PapersPMID:38892688

Effect of Encapsulated Purple Garlic Oil on Microvascular Function and the Components of Metabolic Syndrome: A Randomized Placebo-Controlled Study-The ENDOTALLIUM Study.

Nutrients2024The record ↗

  1. Finding, limited evidencelowersC-reactive protein concentration

What moved

1 findingHow to read these marks →
  • “With regard to endothelial-related circulating biomarkers, we found that hs-CRP significantly decreased after five weeks in the purple garlic group compared to the placebo (between-group difference: −1.3 [−2.5 to −0.0] mg/L; p = 0.049).”
    Study
    RCT
    Duration
    5 weeks
    Effect
    −1.3 mean difference, 95% CI −2.5 to 0
    Dose studied
    4 mg purple garlic oil daily for week 1, then 8 mg daily (one capsule twice daily) for four weeks
    Population
    Adults aged 18 to 65 with at least one metabolic syndrome component, untreated for diabetes, hypertension or dyslipidaemia; single-blind, parallel groups

Study record

Design
randomised controlled trial
Species
human
Population
Men and women aged 18-65 years with at least one metabolic syndrome component, untreated for diabetes, hypertension or dyslipidemia, Hospital Universitario Ramon y Cajal, Madrid
Participants
52
Comparator
placebo
Duration
35 days
Endpoints measured
17