Papers/PMID:38649257
Gastrointestinal effects of caffeine in preterm infants: a systematic review and Bayesian meta-analysis.
Archives of disease in childhood. Fetal and neonatal edition2024The record
1 finding drawn from this paper, on 1 compound across 1 endpoint, 1 of them null.
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
caffeine — no detected effect on necrotising enterocolitis incidence
PreliminaryGrade D, Preliminary. Non-human or in vitro only.FindingNull result“Seven trials assessing necrotising enterocolitis and four trials assessing feeding intolerance in our meta-analysis found no differences between caffeine and placebo (OR=1.007 (95% credible interval 0.021, 5.462), I2=97.4%, and OR=1.266 (95% credible interval 0.064, 28.326), I2=84.8%, respectively).”
Quoted verbatim from Gastrointestinal effects of caffeine in preterm infants: a systematic review and Bayesian meta-analysis.. - Study
- meta-analysis
- Population
- preterm infants; necrotising enterocolitis endpoint, 7 of 9 trials (Bayesian meta-analysis)
Effect 1.007 odds ratio, 95% CI 0.021 to 5.462
Gastrointestinal effects of caffeine in preterm infants: a systematic review and Bayesian meta-analysis.2024PMID:38649257