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PapersPMID:37196876

Whey Protein Supplementation with or without Vitamin D on Sarcopenia-Related Measures: A Systematic Review and Meta-Analysis.

Advances in nutrition (Bethesda, Md.)2023The record ↗

findings
2
compound
1
endpoints
2
no difference found
1
  1. Finding, moderate evidenceraisesPhysical performance
  2. Finding, moderate evidenceno difference foundFat mass
Study, every finding
meta-analysis
Dose studied, every finding
15 to 40 g/day of whey protein across the whey-alone trials
  • “The analysis revealed that whey protein supplementation improved physical performance (SMD = 0.561; 95% CI: 0.256, 0.865; n = 33) (Table 4; Figure 3 and Supplemental Figure S13).”
    Effect
    0.561 standardised mean difference, 95% CI 0.256 to 0.865
    Population
    Older adults aged over 60, healthy and sarcopenic or frail, in randomised trials of whey protein alone; all trials pooled, not a subgroup

What did not

  • “In addition, results showed that supplementation with whey had no significant effect on fat mass (MD = −0.033; 95% CI: −0.465, 0.398; n = 12) (Supplemental Table S11).”
    Effect
    −0.033 mean difference, 95% CI −0.465 to 0.398
    Population
    Older adults aged over 60, healthy and sarcopenic or frail, in randomised trials of whey protein alone; fat mass reported in 14 of the 30 included trials

Study record

Design
meta-analysis
Species
human
Population
Healthy, sarcopenic and frail older adults (>=60 years), 30 RCTs (22 whey protein only, 8 whey protein plus vitamin D)
Participants
not reported
Comparator
an active treatment / placebo
Duration
not reported
Endpoints measured
64
Declined
the paper never states the instrument the node requires