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PapersPMID:36319585

Efficacy of olive leaves extract on the outcomes of hospitalized covid-19 patients: A randomized, triple-blinded clinical trial.

Explore (New York, N.Y.)2023The record ↗

findings
2
compound
1
endpoints
2
  1. Finding, moderate evidencelowersHospital length of stay
  2. Finding, limited evidencelowersC-reactive protein concentration
Study, every finding
RCT · 5 days
Dose studied, every finding
500 mg capsule every 12 hours for 5 days (intervention B)
  • “Additionally, the length of hospitalization for intervention group A (MD=1.75, P<0.001) and intervention group B (MD=1.66, P<0.001) were significantly shorter than the control group.”
    Population
    Hospitalised adults aged 18 to 72 with PCR-confirmed COVID-19 pneumonia, Tehran, Iran; 500 mg arm; all three arms also received dexamethasone, remdesivir, heparin and supplemental oxygen
  • “Furthermore, ESR (MD=14.79, P<0.001) and CRP (MD=16.28, P<0.001) of intervention B were significantly lower than the control group; however, other laboratory tests did not differ (P>0.05).”
    Population
    Hospitalised adults aged 18 to 72 with PCR-confirmed COVID-19 pneumonia, Tehran, Iran; day 5 of hospitalisation, 500 mg arm; all three arms also received dexamethasone, remdesivir, heparin and supplemental oxygen

Study record

Design
randomised controlled trial
Species
human
Population
Hospitalized COVID-19 patients aged 18 to 72 years with PCR-confirmed infection, infectious diseases ward, Labbafinejad Hospital, Tehran, Iran; all received standard COVID-19 treatment
Participants
141
Comparator
placebo
Duration
not reported
Endpoints measured
22