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PapersPMID:36185698

A randomized, double-blind, placebo-controlled trial investigating the effects of an Ocimum tenuiflorum (Holy Basil) extract (HolixerTM) on stress, mood, and sleep in adults experiencing stress.

Frontiers in nutrition2022The record ↗

  1. Finding, moderate evidencelowersPerceived Stress Scale (PSS) score

What moved

1 findingHow to read these marks →
  • “Moreover, from baseline to week 8, there was a statistically significant greater reduction in PSS scores in the Ocimum group compared to the placebo group (p = 0.012).”
    Study
    RCT
    Duration
    8 weeks
    Interests
    Industry funded
    Dose studied
    2 capsules of 62.5 mg extract twice daily for 8 weeks, stated by the paper as delivering 250 mg daily
    Population
    Adults aged 18 to 65 years experiencing stress for longer than a month with sleep problems (PSS 14 or higher), medication free, non-smokers

Study record

Design
randomised controlled trial
Species
human
Population
Adults aged 18 to 65 years experiencing stress for longer than a month and sleep problems, PSS 14 or higher, recruited online in Australia
Participants
100
Comparator
placebo
Duration
56 days
Endpoints measured
58