Papers/PMID:35431994
Efficacy of Resveratrol Supplementation on Glucose and Lipid Metabolism: A Meta-Analysis and Systematic Review.
Frontiers in physiology2022The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
resveratrol — decreases glycated haemoglobin (HbA1c)
LikelyGrade B, Likely. Human evidence with one recorded weakness, or capped at B by its design or by unread numbers.Findingreplicated ×1“There was a significant decrease following RSV administration in WC with an SMD of –0.36 (95% CI: –0.59 to –0.14; P = 0.002; I2 = 88%), hemoglobin A1c (HbA1c): –0.48 (–0.69 to –0.2; P ≤ 0.001; I2 = 94%), TC: –0.15 (–0.3 to –0.01; P = 0.003; I2 = 94%), low-density lipoprotein cholesterol (LDL-C): –0.42 (–0.57 to –0.27; P ≤ 0.001; I2 = 92%), and HDL-C:0.16 (–0.31 to –0.02; P = 0.03; I2 = 81%).”
Quoted verbatim from Efficacy of Resveratrol Supplementation on Glucose and Lipid Metabolism: A Meta-Analysis and Systematic Review.. - Study
- meta-analysis
- Population
- adults, mostly obese and diabetic patients, RSV vs placebo, pooled from 25 RCTs (1,171 participants)
Effect -0.48 standardised mean difference, 95% CI -0.69 to -0.2
Efficacy of Resveratrol Supplementation on Glucose and Lipid Metabolism: A Meta-Analysis and Systematic Review.2022PMID:35431994Permalink
resveratrol — decreases LDL cholesterol
LikelyGrade B, Likely. Human evidence with one recorded weakness, or capped at B by its design or by unread numbers.Findingreplicated ×2“There was a significant decrease following RSV administration in WC with an SMD of –0.36 (95% CI: –0.59 to –0.14; P = 0.002; I2 = 88%), hemoglobin A1c (HbA1c): –0.48 (–0.69 to –0.2; P ≤ 0.001; I2 = 94%), TC: –0.15 (–0.3 to –0.01; P = 0.003; I2 = 94%), low-density lipoprotein cholesterol (LDL-C): –0.42 (–0.57 to –0.27; P ≤ 0.001; I2 = 92%), and HDL-C:0.16 (–0.31 to –0.02; P = 0.03; I2 = 81%).”
Quoted verbatim from Efficacy of Resveratrol Supplementation on Glucose and Lipid Metabolism: A Meta-Analysis and Systematic Review.. - Study
- meta-analysis
- Population
- adults, mostly obese and diabetic patients, RSV vs placebo, pooled from 25 RCTs (1,171 participants)
Effect -0.42 standardised mean difference, 95% CI -0.57 to -0.27
Efficacy of Resveratrol Supplementation on Glucose and Lipid Metabolism: A Meta-Analysis and Systematic Review.2022PMID:35431994Permalink