Papers/PMID:34819636
Gabapentin and pregabalin in bipolar disorder, anxiety states, and insomnia: Systematic review, meta-analysis, and rationale.
Molecular psychiatry2022The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
gabapentin — decreases anxiety symptom severity (pooled across unnamed instruments)
LikelyGrade B, Likely. Human evidence with one recorded weakness, or capped at B by its design or by unread numbers.Finding“Compared with placebo, both pregabalin (SMD -0.55, 95% CI -0.92 to -0.18) and gabapentin (SMD -0.92, 95% CI -1.32 to -0.52) were significantly more effective in reducing preoperative anxiety.”
Quoted verbatim from Gabapentin and pregabalin in bipolar disorder, anxiety states, and insomnia: Systematic review, meta-analysis, and rationale.. - Study
- meta-analysis
- Population
- adult surgical patients with preoperative anxiety, pooled double-blind RCTs of gabapentin versus placebo
Effect -0.92 standardised mean difference, 95% CI -1.32 to -0.52
Gabapentin and pregabalin in bipolar disorder, anxiety states, and insomnia: Systematic review, meta-analysis, and rationale.2022PMID:34819636An author is affiliated with a producerPermalink