Papers/PMID:34684565
Vitamin C in Critically Ill Patients: An Updated Systematic Review and Meta-Analysis.
Nutrients2021The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
L-ascorbic acid — decreases intensive care unit length of stay
StrongEvidence strength: strong. Randomised human trials or their synthesis, with the effect's size and interval recorded and no recorded weakness outstanding.Finding“Polling data from 30 studies reporting the length of ICU stay outcome using a random effect model showed an overall mean difference of −0.76 days, indicating a 0.76-day shorter ICU stay among the vitamin C group compared with placebo/SOC (95% CI, 95% CI, −1.34 to −0.19; n = 252,897; I2 = 96%; p = 0.009).”
Quoted verbatim from Vitamin C in Critically Ill Patients: An Updated Systematic Review and Meta-Analysis.. - Study
- meta-analysis
- Participants
- 252,897
- Population
- Critically ill adults; pooled randomized and observational studies of intravenous vitamin C alone or with other antioxidants versus placebo or standard of care
Effect -0.76 mean difference, 95% CI -1.34 to -0.19
Vitamin C in Critically Ill Patients: An Updated Systematic Review and Meta-Analysis.2021PMID:34684565Permalink