Skip to content
Catalyst

PapersPMID:34578932

Effect of Spirulina Supplementation on Systolic and Diastolic Blood Pressure: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Nutrients2021The record ↗

findings
2
compound
1
endpoints
2
  1. Finding, moderate evidencelowersSystolic blood pressure
  2. Finding, moderate evidencelowersDiastolic blood pressure
Study, every finding
meta-analysis
Dose studied, every finding
1 to 8 g per day
  • “Pooled analysis revealed that Spirulina intake led to a significant lowering of SBP (MD: −4.59 mmHg, 95% CI: −8.20 to −0.99, I2 = 65%).”
    Effect
    −4.59 mean difference, 95% CI −8.2 to −0.99
    Population
    Adults with co-existing disease (hypertension, type 2 diabetes, chronic joint pain, ulcerative colitis) in 5 parallel-group randomised trials of spirulina; four used placebo and one no intervention as control
  • “Pooled analysis of 4 RCTs showed that Spirulina intake significantly lowered DBP (MD: −4.29 mmHg, CI: −8.43 to −0.14, I2 = 81%) in comparison with the control group.”
    Effect
    −4.29 mean difference, 95% CI −8.43 to −0.14
    Population
    Adults with co-existing disease in 4 randomised trials of spirulina with diastolic data; all-trials pool before the sensitivity exclusion

Study record

Design
meta-analysis
Species
human
Population
Adults in 5 parallel-group RCTs of Spirulina, with hypertension, type 2 diabetes mellitus, chronic joint pain or ulcerative colitis
Participants
230
Comparator
placebo
Duration
not reported
Endpoints measured
9