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Catalyst

PapersPMID:34565081

Apple or apple polyphenol consumption improves cardiovascular disease risk factors: a systematic review and meta-analysis.

Reviews in cardiovascular medicine2021The record ↗

  1. Finding, very limited evidencelowersC-reactive protein concentration

What moved

1 findingHow to read these marks →
  • “The meta-analysis showed that the group with apple or apple polyphenol intake had significantly higher high-density lipoprotein levels (standardized mean difference [SMD] = 0.34, 95% confidence interval [CI] [0.01, 0.67], p = 0.0411, I2 = 77%, random-effects model) and significantly lower C-reactive protein levels (SMD = -0.43, 95% CI [-0.65, -0.20], p = 0.0002, I2 = 18%, fixed-effects model) than the control group, indicating that the intervention reduced the risk of cardiovascular diseases.”
    Study
    meta-analysis
    Effect
    −0.43 standardised mean difference, 95% CI −0.65 to −0.2
    Population
    Adults in randomised controlled trials of apple or apple polyphenol intake lasting more than one week, pooled

Study record

Design
meta-analysis
Species
human
Population
randomized controlled trials of apple or apple polyphenol intervention (>1 week) that measured blood pressure, cholesterol and blood glucose
Participants
not reported
Comparator
not stated in the paper / placebo
Duration
not reported
Endpoints measured
2