PapersPMID:34559859
Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis.
No finding here moved its endpoint.
What did not
1 findingHow to read these marks →“However, there was no significant effect of Ashwagandha extract compared to placebo in improving Pittsburgh Sleep Quality Index (SMD -0.90; 95% CI -2.13 to 0.33; I2 = 90%; p = 0.150; two trials; 131 participants), and total time in bed (SMD -0.17; 95% CI -0.41 to 0.07; I2 = 0%; p = 0.170; three trials; 281 participants).”
- Study
- meta-analysis
- Participants
- 131
- Effect
- −0.9 standardised mean difference, 95% CI −2.13 to 0.33
- Dose studied
- 600 mg/day (Table 1, the two trials reporting PSQI)
- Population
- Adults in randomised placebo-controlled trials pooled in a meta-analysis; PSQI reported by two of the five trials (one in adults with insomnia, one in healthy adults and adults with insomnia)
Study record
- Design
- meta-analysis
- Species
- human
- Population
- Adults 18 years and older, healthy or with DSM-IV insomnia, in five Indian RCTs of Withania somnifera extract versus placebo (KSM-66 root extract in four trials, Shoden root and leaf extract in one); one trial partially sponsored by the manufacturer
- Participants
- 400
- Comparator
- placebo
- Duration
- not reported
- Endpoints measured
- 20