PapersPMID:34255069
Suppression of Energy Intake by Intragastric l-Tryptophan in Lean and Obese Men: Relations with Appetite Perceptions and Circulating Cholecystokinin and Tryptophan.
What moved
1 findingHow to read these marks →- Decreases ad libitum test-meal energy intake
very limited
“Trp suppressed energy intake (P < 0.001), with no difference between groups (lean, C: 1085 ± 102 kcal, Trp-1.5: 1009 ± 92 kcal, Trp-3: 868 ± 104 kcal; obese, C: 1249 ± 98 kcal, Trp-1.5: 1217 ± 90 kcal, Trp-3: 1012 ± 100 kcal).”
- Study
- crossover
- Dose studied
- single intragastric load of 3 g or 1.5 g Trp, 30 min before a buffet meal, versus control
- Population
- Twelve lean men and 13 men with obesity; double-blind randomized crossover; buffet-meal energy intake 30 min after intragastric Trp; primary outcome; groups did not differ
Study record
- Design
- crossover trial
- Species
- human
- Population
- 12 lean men and 13 men with obesity; intragastric L-tryptophan 1.5 g and 3 g against intragastric control, 30 min before a buffet-meal
- Participants
- 25
- Comparator
- placebo
- Duration
- not reported
- Endpoints measured
- 19