PapersPMID:33782820
A systematic review for the efficacy of coenzyme Q10 in patients with chronic kidney disease.
- findings
- 5
- compound
- 1
- endpoints
- 5
- no difference found
- 4
- Study, every finding
- meta-analysis
- Population, every finding
- adults with chronic kidney disease (CKD); meta-analysis of 12 studies (17 publications)
What moved
How to read these marks →- Decreases C-reactive protein concentration
very limitedreplicated ×3
“Regarding oxidative stress and inflammation, pooled analysis showed that CoQ10 supplementation significantly reduced malonaldehyde (WMD: - 1.15 95% CI - 1.48 to - 0.81) and high-sensitivity C reactive protein levels (WMD: - 1.18 95% CI - 2.21 to - 0.15).”
- Effect
- −1.18 mean difference, 95% CI −2.21 to −0.15
What did not
“The pooled results indicated that CoQ10 supplementation had no effects on total cholesterol, or LDL-cholesterol, or on HDL-cholesterol, and triglycerides.”
- No detected effect on LDL cholesterol
very limited
- No detected effect on triglycerides
very limitedreplicated ×2
- No detected effect on HDL cholesterol
very limitedreplicated ×3
- No detected effect on total cholesterol (TC)
very limitedreplicated ×2
Study record
- Design
- meta-analysis
- Species
- human
- Population
- adults with chronic kidney disease (CKD)
- Participants
- not reported
- Comparator
- none
- Duration
- not reported
- Endpoints measured
- 6