Papers/PMID:33782820
A systematic review for the efficacy of coenzyme Q10 in patients with chronic kidney disease.
International urology and nephrology2022The record
5 findings · 1 compound · 5 endpoints · 4 null
What it reported
How to read these marksWhat moved
1 finding
coenzyme Q10 — decreases C-reactive protein concentration
PreliminaryGrade D, Preliminary. Non-human or in vitro only.Findingreplicated ×3“Regarding oxidative stress and inflammation, pooled analysis showed that CoQ10 supplementation significantly reduced malonaldehyde (WMD: - 1.15 95% CI - 1.48 to - 0.81) and high-sensitivity C reactive protein levels (WMD: - 1.18 95% CI - 2.21 to - 0.15).”
Quoted verbatim from A systematic review for the efficacy of coenzyme Q10 in patients with chronic kidney disease.. - Study
- meta-analysis
- Population
- adults with chronic kidney disease (CKD); meta-analysis of 12 studies (17 publications)
Effect -1.18 mean difference, 95% CI -2.21 to -0.15
A systematic review for the efficacy of coenzyme Q10 in patients with chronic kidney disease.2022PMID:33782820Permalink
What did not
4 findings
coenzyme Q10 — no detected effect on total cholesterol (TC)
PreliminaryGrade D, Preliminary. Non-human or in vitro only.FindingNull resultreplicated ×1“The pooled results indicated that CoQ10 supplementation had no effects on total cholesterol, or LDL-cholesterol, or on HDL-cholesterol, and triglycerides.”
Quoted verbatim from A systematic review for the efficacy of coenzyme Q10 in patients with chronic kidney disease.. - Study
- meta-analysis
- Population
- adults with chronic kidney disease (CKD); meta-analysis of 12 studies (17 publications)
A systematic review for the efficacy of coenzyme Q10 in patients with chronic kidney disease.2022PMID:33782820Permalink
coenzyme Q10 — no detected effect on LDL cholesterol
PreliminaryGrade D, Preliminary. Non-human or in vitro only.FindingNull resultreplicated ×1“The pooled results indicated that CoQ10 supplementation had no effects on total cholesterol, or LDL-cholesterol, or on HDL-cholesterol, and triglycerides.”
Quoted verbatim from A systematic review for the efficacy of coenzyme Q10 in patients with chronic kidney disease.. - Study
- meta-analysis
- Population
- adults with chronic kidney disease (CKD); meta-analysis of 12 studies (17 publications)
A systematic review for the efficacy of coenzyme Q10 in patients with chronic kidney disease.2022PMID:33782820Permalink
coenzyme Q10 — no detected effect on HDL cholesterol
PreliminaryGrade D, Preliminary. Non-human or in vitro only.FindingNull resultreplicated ×2“The pooled results indicated that CoQ10 supplementation had no effects on total cholesterol, or LDL-cholesterol, or on HDL-cholesterol, and triglycerides.”
Quoted verbatim from A systematic review for the efficacy of coenzyme Q10 in patients with chronic kidney disease.. - Study
- meta-analysis
- Population
- adults with chronic kidney disease (CKD); meta-analysis of 12 studies (17 publications)
A systematic review for the efficacy of coenzyme Q10 in patients with chronic kidney disease.2022PMID:33782820Permalink
coenzyme Q10 — no detected effect on triglycerides
PreliminaryGrade D, Preliminary. Non-human or in vitro only.FindingNull resultreplicated ×1“The pooled results indicated that CoQ10 supplementation had no effects on total cholesterol, or LDL-cholesterol, or on HDL-cholesterol, and triglycerides.”
Quoted verbatim from A systematic review for the efficacy of coenzyme Q10 in patients with chronic kidney disease.. - Study
- meta-analysis
- Population
- adults with chronic kidney disease (CKD); meta-analysis of 12 studies (17 publications)
A systematic review for the efficacy of coenzyme Q10 in patients with chronic kidney disease.2022PMID:33782820Permalink