Papers/PMID:33482034
Effect of atorvastatin on testosterone levels.
The Cochrane database of systematic reviews2021The record
2 findings · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksWhat moved
1 finding
atorvastatin — decreases total testosterone
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“In females with PCOS, atorvastatin lowered the total testosterone, FAI, androstenedione, and DHEAS.”
Quoted verbatim from Effect of atorvastatin on testosterone levels.. - Study
- meta-analysis
- Population
- Females with polycystic ovary syndrome in four randomised trials (mean age 32 years), atorvastatin daily for at least three weeks versus placebo or no treatment
Effect of atorvastatin on testosterone levels.2021PMID:33482034Permalink
What did not
1 finding
atorvastatin — no detected effect on total testosterone
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“We found no significant difference between atorvastatin and placebo on the levels of total testosterone in males.”
Quoted verbatim from Effect of atorvastatin on testosterone levels.. - Study
- meta-analysis
- Population
- Males in two randomised trials (normal lipid profile or mild dyslipidaemia; mean age 68 years), atorvastatin daily for at least three weeks versus placebo or no treatment
Effect of atorvastatin on testosterone levels.2021PMID:33482034Permalink