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PapersPMID:33123091

Iodine Supplementation in Mildly Iodine-Deficient Pregnant Women Does Not Improve Maternal Thyroid Function or Child Development: A Secondary Analysis of a Randomized Controlled Trial.

Frontiers in endocrinology2020The record ↗

iodide

lowersSerum free thyroxine (FT4)

What moved

1 findingHow to read these marks →

Decreases serum free thyroxine (FT4)
moderate
“During pregnancy, maternal free and total thyroxine concentrations were lower in the iodine group as compared to placebo (p = 0.0003, and p = 0.02, respectively).”
Study
RCT
Dose studied
200 μg iodine daily as potassium iodide tablets until delivery
Population
Mildly iodine-deficient pregnant women in Bangkok, Thailand (median urinary iodine 112 µg/L at entry, gestational age 14 weeks or less), measured in the 2nd and 3rd trimesters; about 88% of households in both arms used iodised salt

Study record

Design: randomised controlled trial
Species: human
Population: mildly iodine-deficient Thai pregnant women in Bangkok and their children
Participants: 514
Comparator: placebo
Duration: not reported
Endpoints measured: 100