Papers/PMID:32579292
Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology2020The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
all-cis-5,8,11,14,17-icosapentaenoic acid — decreases HOMA-IR
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Findingreplicated ×1“The HOMA‐IR score was also lowered with EPA in the diet, relative to the mice consuming the HF diet.”
Quoted verbatim from Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner.. - Study
- animal · not in humans
- Duration
- 3 months
- Dose
- EPA ethyl esters (Cayman, at least 93% pure) in the high-fat diet, 2% of total energy; the paper states pure EPA ethyl esters were used, not mixtures with DHA
- Population
- Male C57BL/6J mice fed a high-fat diet (60% kcal from lard) for 15 weeks, with or without EPA ethyl esters
Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner.2020PMID:32579292Permalink