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PapersPMID:32276466

Immunological Outcomes of Bovine Colostrum Supplementation in Trained and Physically Active People: A Systematic Review and Meta-Analysis.

Nutrients2020The record ↗

  1. Finding, moderate evidenceno difference foundSalivary immunoglobulin A (IgA) concentration

No finding here moved its endpoint.

What did not

1 findingHow to read these marks →
  • No detected effect on salivary immunoglobulin A (IgA) concentration

    moderate

    “Nevertheless, pooled analyses from the nine trials demonstrated a non-significant effect of BC supplementation on the SIgA concentration (g Hedges 0.15, 95% confidence −0.20 to 0.49, p value 0.4033).”
    Study
    meta-analysis
    Effect
    0.15 standardised mean difference, 95% CI −0.2 to 0.49
    Dose studied
    10 to 25 g/day powder or 25/125 ml liquid per day, 8 days to 12 weeks (range across pooled trials)
    Population
    Trained and physically active adults (athletes and recreationally active, about 82% male); pooled pre-exercise estimate, bovine colostrum versus placebo

Study record

Design
meta-analysis
Species
human
Population
trained and physically active adults supplemented with bovine colostrum (powder or liquid) versus placebo; ten RCTs
Participants
239
Comparator
placebo
Duration
not reported
Endpoints measured
8
Declined
this platform holds no node for the endpoint