Papers/PMID:32243377
Efficacy and tolerability of paroxetine in adults with social anxiety disorder: A meta-analysis of randomized controlled trials.
Medicine2020The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
paroxetine — increases withdrawal due to adverse events
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“Discontinuation rate due to AEs was higher in paroxetine group than placebo group (OR = 3.41, 95%CI 2.45–4.72, P <.00001) whereas the rate due to lack of efficacy was higher in placebo group as compared with paroxetine group (OR = 0.14, 95%CI 0.09–0.22, P <.00001).”
Quoted verbatim from Efficacy and tolerability of paroxetine in adults with social anxiety disorder: A meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Dose
- fixed 20, 40 or 60 mg/day, or flexible 12.5 to 60 mg/day
- Population
- Adults with social anxiety disorder in placebo-controlled randomised trials of paroxetine (13 RCTs, 2593 patients)
Effect 3.41 odds ratio, 95% CI 2.45 to 4.72
Efficacy and tolerability of paroxetine in adults with social anxiety disorder: A meta-analysis of randomized controlled trials.2020PMID:32243377Permalink