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PapersPMID:31694759

Medium-chain triglycerides improved cognition and lipid metabolomics in mild to moderate Alzheimer's disease patients with APOE4-/-: A double-blind, randomized, placebo-controlled crossover trial.

Clinical nutrition (Edinburgh, Scotland)2020The record ↗

  1. Finding, very limited evidenceno difference foundActivities of daily living score

No finding here moved its endpoint.

What did not

1 findingHow to read these marks →
  • “Changes in ADL scores were not significantly different between the MCT and placebo interventions (p > 0.05).”
    Study
    crossover
    Duration
    4 weeks
    Dose studied
    MCT jelly by mouth three times daily, total daily fat dose 17.3 g MCT, 30 days per phase
    Population
    Adults with mild to moderate Alzheimer's disease, APOE4-/- subjects who completed the study analysed; MCT jelly versus canola-oil placebo jelly in a double-blind crossover

Study record

Design
crossover trial
Species
human
Population
patients with mild to moderate Alzheimer's disease (APOE4-/- analysed); abstract-only record
Participants
53
Comparator
placebo
Duration
30 days
Endpoints measured
13