Papers/PMID:31337982
Amorphous solid dispersion of Berberine mitigates apoptosis via iPLA2β/Cardiolipin/Opa1 pathway in db/db mice and in Palmitate-treated MIN6 β-cells.
International journal of biological sciences2019The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
berberine — decreases triglycerides
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×2“Furthermore, the FBG, RBG and TG in BBR- and HGSD-treated mice were significantly lower than those in db/db mice, and the OGTT and ITT were significantly improved compared with those in the db/db group.”
Quoted verbatim from Amorphous solid dispersion of Berberine mitigates apoptosis via iPLA2β/Cardiolipin/Opa1 pathway in db/db mice and in Palmitate-treated MIN6 β-cells.. - Study
- animal · not in humans
- Dose
- berberine 160 mg/kg daily for 4 weeks
- Population
- Male db/db mice treated with berberine alone versus saline-treated db/db mice; the sentence pools berberine-treated and Huang-Gui Solid Dispersion-treated mice
Amorphous solid dispersion of Berberine mitigates apoptosis via iPLA2β/Cardiolipin/Opa1 pathway in db/db mice and in Palmitate-treated MIN6 β-cells.2019PMID:31337982Permalink