Papers/PMID:31249528
The Effects of Curcumin on Weight Loss Among Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Frontiers in pharmacology2019The record
3 findings · 1 compound · 3 endpoints
What it reported
How to read these marksWhat moved
3 findings
curcumin — decreases body mass index
LikelyGrade B, Likely. Human evidence with one recorded weakness, or capped at B by its design or by unread numbers.Findingreplicated ×6“Curcumin resulted a significant reduction in BMI (SMD −0.37; 95% CI, −0.61, −0.13; P < 0.01), weight (SMD −0.23; 95% CI, −0.39, −0.06; P < 0.01), and WC levels (SMD −0.25; 95% CI, −0.44, −0.05; P = 0.01).”
Quoted verbatim from The Effects of Curcumin on Weight Loss Among Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.. - Study
- meta-analysis
- Population
- patients with metabolic syndrome and related disorders, compared to placebo (pooled random-effects meta-analysis)
Effect -0.37 standardised mean difference, 95% CI -0.61 to -0.13
The Effects of Curcumin on Weight Loss Among Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.2019PMID:31249528Permalink
curcumin — decreases serum leptin
LikelyGrade B, Likely. Human evidence with one recorded weakness, or capped at B by its design or by unread numbers.Findingreplicated ×3“The results showed that curcumin intake among individuals with metabolic diseases significantly reduced leptin (SMD −0.97; 95% CI, −1.18, −0.75; P < 0.001) and increased adiponectin levels (SMD 1.05; 95% CI, 0.23, 1.87; P = 0.01).”
Quoted verbatim from The Effects of Curcumin on Weight Loss Among Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.. - Study
- meta-analysis
- Population
- individuals with metabolic diseases, compared to placebo (pooled meta-analysis)
Effect -0.97 standardised mean difference, 95% CI -1.18 to -0.75
The Effects of Curcumin on Weight Loss Among Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.2019PMID:31249528Permalink
curcumin — decreases body mass
SuggestiveGrade C, Suggestive. Human evidence with several recorded weaknesses, or a design that tops out at C.Findingreplicated ×1“Curcumin resulted a significant reduction in BMI (SMD −0.37; 95% CI, −0.61, −0.13; P < 0.01), weight (SMD −0.23; 95% CI, −0.39, −0.06; P < 0.01), and WC levels (SMD −0.25; 95% CI, −0.44, −0.05; P = 0.01).”
Quoted verbatim from The Effects of Curcumin on Weight Loss Among Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.. - Study
- meta-analysis
- Population
- patients with metabolic syndrome and related disorders, compared to placebo (pooled random-effects meta-analysis)
Effect -0.23 standardised mean difference, 95% CI -0.39 to -0.06
The Effects of Curcumin on Weight Loss Among Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.2019PMID:31249528Permalink