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Catalyst

PapersPMID:30771686

Fish Oil Increases Specialized Pro-resolving Lipid Mediators in PAD (The OMEGA-PAD II Trial).

The Journal of surgical research2019The record ↗

  1. Finding, moderate evidenceraisesOmega-3 index (erythrocyte membrane)

What moved

1 findingHow to read these marks →
  • “However, the omega-3 index increased more than two-fold in the fish oil group only (7.2 ± 1.2% increase from baseline, P < 0.001; between group differential P < 0.001).”
    Study
    RCT
    Dose studied
    4.4 g/day, four capsules twice daily, for 3 months
    Population
    Male veterans aged 50 years or older with peripheral artery disease and intermittent claudication (11 randomised to fish oil, 13 to soybean oil placebo), after 3 months

Study record

Design
randomised controlled trial
Species
human
Population
Male veterans with peripheral artery disease and intermittent claudication (Rutherford I-III), San Francisco VA Medical Center; fish oil (ProOmega, ethyl-ester/triglyceride form not stated) versus soybean oil placebo
Participants
24
Comparator
placebo
Duration
91 days
Endpoints measured
21