Papers/PMID:30662584
Hypoglycemic Mechanism of the Berberine Organic Acid Salt under the Synergistic Effect of Intestinal Flora and Oxidative Stress.
Oxidative medicine and cellular longevity2018The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
- Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×3
“As shown in Figure 1, BF treatment significantly increased plasma FINS, T-SOD, GSH-PX, and GLP-1 and reduced FBG, HOMA-IR, and plasma TG, TC, and GSP (all P < 0.05) in diabetic rats.”
Quoted verbatim from Hypoglycemic Mechanism of the Berberine Organic Acid Salt under the Synergistic Effect of Intestinal Flora and Oxidative Stress.. - Study
- animal · not in humans
- Dose
- 500 mg/kg per day berberine fumarate by intragastric administration for 4 weeks
- Population
- Streptozotocin plus high-fat high-sucrose diet type 2 diabetic Sprague-Dawley rats given berberine fumarate versus distilled-water-treated diabetic rats
Hypoglycemic Mechanism of the Berberine Organic Acid Salt under the Synergistic Effect of Intestinal Flora and Oxidative Stress.2018PMID:30662584Permalink