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Catalyst

PapersPMID:30477853

Vitamin B12 for herpetic neuralgia: A meta-analysis of randomised controlled trials.

Complementary therapies in medicine2018The record ↗

findings
2
compound
1
endpoints
2
  1. Finding, very limited evidencelowersNumeric rating scale (NRS) pain intensity
  2. Finding, very limited evidenceraisesHealth-related quality of life
Study, every finding
meta-analysis
Population, every finding
Patients with postherpetic neuralgia; pooled randomised trials of vitamin B12 against placebo
  • “Compared with the placebo group, the Vitamin B12 group exhibited a significant decrease in the Numeric Rating Scale score, with a mean difference of -4.01 (95% confidence interval = -4.70 to -3.33).”
    Effect
    −4.01 mean difference, 95% CI −4.7 to −3.33
  • “Vitamin B12 administration improved the quality of life of PHN patients with moderate quality evidence and significantly decreased the number of patients using analgesics.”

Study record

Design
meta-analysis
Species
human
Population
Patients with postherpetic neuralgia (PHN)
Participants
383
Comparator
placebo
Duration
not reported
Endpoints measured
1