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PapersPMID:30400924

Effects of green tea extract on overweight and obese women with high levels of low density-lipoprotein-cholesterol (LDL-C): a randomised, double-blind, and cross-over placebo-controlled clinical trial.

BMC complementary and alternative medicine2018The record ↗

findings
2
compound
1
endpoints
2
  1. Finding, moderate evidenceno difference foundTriglycerides
  2. Finding, moderate evidenceno difference foundBody mass index
Study, every finding
crossover · 6 weeks
Dose studied, every finding
One capsule 30 minutes after meals three times daily for 6 weeks; daily EGCG 856.8 mg
Population, every finding
Overweight and obese Taiwanese women aged 18-65 years with BMI 27 or above and LDL-C 130 mg/dL or above; 6-week treatment stages separated by a 14-day washout

No finding here moved its endpoint.

  • “The double-blind, placebo-controlled, cross-over design study showed that there were no statistical difference in the levels of BMI, fasting blood sugar, total cholesterol, triglyceride, high density lipoprotein, adiponectin and ghrelin etc. between the GTE and placebo groups after treatments.”

Study record

Design
crossover trial
Species
human
Population
Overweight and obese Taiwanese women (BMI >= 27 kg/m2) with LDL-C >= 130 mg/dl; green tea extract (EGCG-rich, from dried green tea leaves) versus microcrystalline cellulose placebo
Participants
73
Comparator
placebo
Duration
42 days
Endpoints measured
37