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PapersPMID:29747663

The lipid-lowering effects of Danhong and Huangqi injections: a meta-analysis of clinical controlled trials.

Lipids in health and disease2018The record ↗

findings
3
compound
1
endpoints
3
no difference found
2
PMID:29747663
  1. Finding, moderate evidencelowersTotal cholesterol (TC)
  2. Finding, moderate evidenceno difference foundLDL cholesterol
  3. Finding, moderate evidenceno difference foundHDL cholesterol
Study, every finding
meta-analysis
  • “The outcomes of the analysis on all studies showed that Huangqi injection could significantly decrease TC levels [SMD = − 1.13, 95% CI = (− 2.09, − 0.16), P = 0.02], and marginally significantly decrease TG levels [SMD = − 1.27, 95% CI = (− 2.53, 0.00), P = 0.05].”
    Effect
    −1.13 standardised mean difference, 95% CI −2.09 to −0.16
    Dose studied
    high dose (40 mL or more) in 4 trials, low dose (under 40 mL) in 3 trials
    Population
    Meta-analysis of 7 controlled trials (542 subjects, all Chinese, 5 of the 7 in nephrotic syndrome) of Huangqi injection added to control treatment versus control treatment alone

What did not

  • “Huangqi injection did not have significant effects on the changes in LDL-C and HDL-C levels (Table 2 and Fig. 5).”
    • Population
      Meta-analysis of 3 controlled trials (220 subjects, all Chinese) of Huangqi injection added to control treatment versus control treatment alone
    • Population
      Meta-analysis of 3 controlled trials (220 subjects, all Chinese) of Huangqi injection added to control treatment versus control treatment alone

Study record

Design
meta-analysis
Species
human
Population
Chinese subjects with coronary heart disease, stroke, hyperlipidemia, diabetes, nephrotic syndrome or hypertension
Participants
not reported
Comparator
no treatment
Duration
not reported
Endpoints measured
50