Papers/PMID:29049383
Lutein accumulates in subcellular membranes of brain regions in adult rhesus macaques: Relationship to DHA oxidation products.
PloS one2017The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
lutein — accumulates in cerebellum
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“In PFC and CER, lutein concentrations were significantly greater in L/Z supplemented monkeys compared to monkeys fed stock diet alone (P<0.05).”
Quoted verbatim from Lutein accumulates in subcellular membranes of brain regions in adult rhesus macaques: Relationship to DHA oxidation products.. - Study
- animal · not in humans
- Dose
- about 4.5 mg lutein and 0.5 mg zeaxanthin per day over a stock diet with about 2 mg lutein per day, 6 to 12 months
- Population
- Adult rhesus macaques, lutein plus zeaxanthin supplement (n = 4) versus stock diet alone (n = 9); trans-lutein in brain region homogenate by HPLC
Lutein accumulates in subcellular membranes of brain regions in adult rhesus macaques: Relationship to DHA oxidation products.2017PMID:29049383Industry fundedPermalink
lutein — accumulates in prefrontal cortex
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“In PFC and CER, lutein concentrations were significantly greater in L/Z supplemented monkeys compared to monkeys fed stock diet alone (P<0.05).”
Quoted verbatim from Lutein accumulates in subcellular membranes of brain regions in adult rhesus macaques: Relationship to DHA oxidation products.. - Study
- animal · not in humans
- Dose
- about 4.5 mg lutein and 0.5 mg zeaxanthin per day over a stock diet with about 2 mg lutein per day, 6 to 12 months
- Population
- Adult rhesus macaques, lutein plus zeaxanthin supplement (n = 4) versus stock diet alone (n = 9); trans-lutein in brain region homogenate by HPLC
Lutein accumulates in subcellular membranes of brain regions in adult rhesus macaques: Relationship to DHA oxidation products.2017PMID:29049383Industry fundedPermalink